Cyanacetic acid CAS number: 372-09-8
Application areas: pharmaceutical and pesticide intermediates, such as fungicide cymoxanil, pharmaceutical caffeine, vitamin B6, etc.
Product specifications
Content: 70%±1%
Water content: 10%-30%
Main packaging: 200KG plastic barrel, 1000L IBC barrel or ISO container tank.
Applications:
Cyanoacetic acid is used as a reagent in the following reactions:
It is used together with acetic anhydride for the cyanoacetylation of various pyrrole, indole and aniline derivatives. It is also used in other reactions such as cyclization, synthesis of coumarins and other heterocycles.
It is a key intermediate in the total synthesis of 5-acetamido-substituted melatonin derivatives that can serve as MT3 receptor ligands by Knoevenagel condensation.
Synthesis of aminopyrrolinone derivatives by reaction of Ugi adducts with cyanoacetic acid and aromatic aldehydes.